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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Marty Bystrom# | 3995.1 | 1980-1998 | |
| 2 | Bill Gullickson | 3859.2 | 1979-1996 | |
| 3 | Dwight Gooden# | 3715.0 | 1984-1998 | |
| 4 | Matt Young# | 3614.1 | 1983-1998 | |
| 5 | Bret Saberhagen# | 3443.2 | 1984-1998 | |
| 6 | Dennis Eckersley | 3385.1 | 1976-1993 | |
| 7 | Jose Rijo# | 3372.0 | 1984-1998 | |
| 8 | Jon Matlack* | 3346.0 | 1976-1990 | |
| 9 | Jose DeLeon# | 3341.0 | 1983-1997 | |
| 10 | Silvio Martinez | 3310.2 | 1977-1993 | |
| 11 | Kevin Brown# | 3306.1 | 1986-1998 | |
| 12 | John Fulgham | 3254.0 | 1979-1994 | |
| 13 | Joe Johnson# | 3222.0 | 1985-1998 | |
| 14 | Floyd Youmans# | 3217.1 | 1985-1998 | |
| 15 | Ron Robinson# | 3180.1 | 1984-1998 | |
| 16 | Vida Blue* | 3165.0 | 1976-1990 | |
| 17 | Roger Erickson | 3133.1 | 1978-1992 | |
| 18 | Mike Scott | 3120.1 | 1979-1992 | |
| 19 | Orel Hershiser# | 3091.2 | 1983-1996 | |
| 20 | Scott Sanderson | 3088.1 | 1978-1992 | |
| 21 | Jimmy Key# | 3040.2 | 1984-1997 | |
| 22 | Roger Clemens# | 3029.0 | 1984-1998 | |
| 23 | Greg Maddux# | 2991.1 | 1986-1998 | |
| 24 | Bob Sebra# | 2986.1 | 1985-1998 | |
| 25 | Scott Garrelts# | 2975.1 | 1982-1998 | |
| 26 | John Butcher | 2972.0 | 1980-1994 | |
| 27 | Bob Ojeda# | 2898.2 | 1982-1998 | |
| 28 | John Candelaria | 2880.0 | 1976-1990 | |
| 29 | Jeff D. Robinson# | 2873.1 | 1984-1998 | |
| 30 | Rick Rhoden | 2866.2 | 1976-1992 | |
| 31 | Zane Smith# | 2819.0 | 1984-1997 | |
| 32 | Mike Morgan# | 2809.0 | 1979-1995 | |
| 33 | Mike LaCoss | 2786.2 | 1978-1991 | |
| 34 | Jack Morris | 2785.0 | 1977-1990 | |
| 35 | Bruce Hurst | 2774.0 | 1982-1994 | |
| 36 | Mark Fidrych | 2754.2 | 1976-1988 | |
| 37 | John Tudor | 2693.0 | 1979-1992 | |
| 38 | Teddy Higuera# | 2646.1 | 1985-1998 | |
| 39 | Frank Viola# | 2645.0 | 1982-1994 | |
| 40 | Bruce Ruffin# | 2642.1 | 1986-1998 | |
| 41 | Andy Rincon | 2632.1 | 1980-1994 | |
| 42 | John Smiley# | 2611.0 | 1986-1998 | |
| 43 | Kelly Downs# | 2588.2 | 1986-1998 | |
| 44 | Dan Warthen | 2581.2 | 1976-1992 | |
| 45 | Tony Brizzolara | 2558.1 | 1980-1991 | |
| 46 | John Burkett# | 2541.0 | 1987-1998 | |
| 47 | Danny Jackson | 2531.0 | 1983-1996 | |
| 48 | Pascual Perez | 2530.1 | 1980-1993 | |
| 49 | Charlie Leibrandt | 2503.0 | 1979-1990 | |
| 50 | Ed Correa# | 2489.2 | 1985-1998 | |
| 51 | Jay Tibbs# | 2486.1 | 1984-1998 | |
| 52 | Jamie Moyer# | 2485.0 | 1987-1998 | |
| 53 | Atlee Hammaker | 2461.0 | 1981-1991 | |
| 54 | Dave Goltz | 2460.2 | 1976-1987 | |
| 55 | David Clyde | 2455.2 | 1976-1990 | |
| 56 | Dennis Martinez | 2451.2 | 1976-1991 | |
| 57 | Eric King# | 2450.1 | 1987-1998 | |
| 58 | Kevin Gross# | 2439.0 | 1983-1997 | |
| 59 | John Montefusco* | 2437.2 | 1976-1985 | |
| 60 | Erik Hanson# | 2432.0 | 1988-1998 | |
| 61 | J.R. Richard | 2416.0 | 1976-1988 | |
| 62 | Randy Johnson# | 2400.0 | 1989-1998 | |
| 63 | Gary Serum | 2392.2 | 1978-1988 | |
| 64 | Mark Guthrie# | 2375.0 | 1989-1998 | |
| 65 | Fernando Valenzuela | 2351.1 | 1980-1993 | |
| 66 | Bill C. Swift | 2331.2 | 1985-1996 | |
| 67 | Mike Parrott | 2328.0 | 1977-1993 | |
| 68 | Scott Bankhead# | 2326.1 | 1986-1998 | |
| 69 | Steve Rogers | 2307.0 | 1976-1988 | |
| 70 | Tom Glavine# | 2298.1 | 1988-1998 | |
| 71 | Frank Pastore | 2255.0 | 1979-1993 | |
| 72 | Doug Drabek# | 2250.2 | 1987-1998 | |
| 73 | Kevin Appier# | 2238.2 | 1989-1998 | |
| 74 | Melido Perez# | 2232.0 | 1987-1998 | |
| 75 | Frank Tanana | 2230.1 | 1976-1988 | |
| 76 | Mike Harkey# | 2228.2 | 1988-1998 | |
| 77 | Dennis Lamp | 2216.1 | 1977-1988 | |
| 78 | Larry McWilliams | 2203.2 | 1978-1989 | |
| 79 | Rick Aguilera# | 2196.0 | 1985-1998 | |
| 80 | Jim Clancy | 2156.2 | 1977-1991 | |
| 81 | John Mitchell# | 2147.0 | 1986-1997 | |
| 82 | Joaquin Andujar | 2139.0 | 1977-1987 | |
| 83 | Wayne Garland | 2133.1 | 1976-1987 | |
| 84 | Dick Ruthven | 2133.0 | 1976-1987 | |
| 85 | Doc Medich | 2131.1 | 1976-1984 | |
| 86 | Ramon J. Martinez# | 2126.0 | 1988-1998 | |
| 86 | Randy Tomlin# | 2126.0 | 1990-1998 | |
| 88 | Rick Reed# | 2111.0 | 1988-1998 | |
| 89 | Mike Mussina# | 2107.2 | 1991-1998 | |
| 90 | Ken Brett | 2100.2 | 1976-1987 | |
| 91 | LaMarr Hoyt | 2074.0 | 1980-1994 | |
| 92 | Wally Whitehurst# | 2037.2 | 1989-1998 | |
| 93 | Jerry Reuss | 2027.0 | 1976-1986 | |
| 94 | Frank Wills# | 2018.0 | 1984-1998 | |
| 95 | Andy Benes# | 2001.1 | 1989-1998 | |
| 96 | Mark Portugal# | 1997.2 | 1985-1998 | |
| 97 | Al Leiter# | 1989.2 | 1988-1998 | |
| 98 | Mark Langston# | 1985.1 | 1984-1997 | |
| 99 | Tim Belcher# | 1977.0 | 1987-1997 | |
| 100 | John Smoltz# | 1972.2 | 1988-1998 |
