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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Dwight Gooden# | 4057 | 1984-1998 | |
| 2 | Floyd Youmans# | 3408 | 1985-1998 | |
| 3 | Randy Johnson# | 3205 | 1989-1998 | |
| 4 | Ed Correa# | 3186 | 1985-1998 | |
| 5 | Kevin Brown# | 3135 | 1986-1998 | |
| 6 | Jose Rijo# | 3066 | 1984-1998 | |
| 7 | Roger Clemens# | 2879 | 1984-1998 | |
| 8 | Greg Maddux# | 2878 | 1986-1998 | |
| 9 | Jose DeLeon# | 2868 | 1983-1997 | |
| 10 | Scott Garrelts# | 2698 | 1982-1998 | |
| 11 | Bob Sebra# | 2689 | 1985-1998 | |
| 12 | Dennis Eckersley | 2671 | 1976-1993 | |
| 13 | Bruce Hurst | 2656 | 1982-1994 | |
| 14 | Matt Young# | 2601 | 1983-1998 | |
| 15 | Bret Saberhagen# | 2552 | 1984-1998 | |
| 16 | Pedro Martinez# | 2462 | 1992-1998 | |
| 17 | Bill Gullickson | 2445 | 1979-1996 | |
| 18 | Teddy Higuera# | 2444 | 1985-1998 | |
| 19 | Ron Robinson# | 2388 | 1984-1998 | |
| 20 | Jon Matlack* | 2330 | 1976-1990 | |
| 21 | Scott Sanderson | 2319 | 1978-1992 | |
| 22 | John Smoltz# | 2285 | 1988-1998 | |
| 23 | Mike Scott | 2253 | 1979-1992 | |
| 24 | Erik Hanson# | 2198 | 1988-1998 | |
| 25 | Marty Bystrom# | 2194 | 1980-1998 | |
| 26 | Orel Hershiser# | 2169 | 1983-1996 | |
| 27 | Jimmy Key# | 2156 | 1984-1997 | |
| 28 | Curt Schilling# | 2123 | 1991-1998 | |
| 29 | Kevin Appier# | 2119 | 1989-1998 | |
| 30 | Al Leiter# | 2105 | 1988-1998 | |
| 31 | John Smiley# | 2052 | 1986-1998 | |
| 32 | Frank Viola# | 2034 | 1982-1994 | |
| 33 | Kelly Downs# | 2030 | 1986-1998 | |
| 34 | Bob Ojeda# | 2026 | 1982-1998 | |
| 35 | Melido Perez# | 1996 | 1987-1998 | |
| 36 | Fernando Valenzuela | 1960 | 1980-1993 | |
| 37 | Mark Guthrie# | 1958 | 1989-1998 | |
| 38 | Scott Bankhead# | 1955 | 1986-1998 | |
| 39 | Jack Morris | 1951 | 1977-1990 | |
| 40 | Dan Warthen | 1931 | 1976-1992 | |
| 41 | John Burkett# | 1929 | 1987-1998 | |
| 42 | Mike Mussina# | 1919 | 1991-1998 | |
| 43 | John Fulgham | 1875 | 1979-1994 | |
| 44 | John Candelaria | 1872 | 1976-1990 | |
| 45 | Mark Langston# | 1853 | 1984-1997 | |
| 46 | Jamie Moyer# | 1851 | 1987-1998 | |
| 46 | Bruce Ruffin# | 1851 | 1986-1998 | |
| 48 | Andy Benes# | 1847 | 1989-1998 | |
| 49 | Danny Jackson | 1843 | 1983-1996 | |
| 50 | John Montefusco* | 1837 | 1976-1985 | |
| 51 | Silvio Martinez | 1816 | 1977-1993 | |
| 52 | Pascual Perez | 1801 | 1980-1993 | |
| 53 | Ramon J. Martinez# | 1800 | 1988-1998 | |
| 54 | Vida Blue* | 1795 | 1976-1990 | |
| 55 | Eric King# | 1761 | 1987-1998 | |
| 56 | Frank Tanana | 1760 | 1976-1988 | |
| 57 | Jeff D. Robinson# | 1750 | 1984-1998 | |
| 58 | Kevin Gross# | 1730 | 1983-1997 | |
| 59 | Rick Reed# | 1688 | 1988-1998 | |
| 60 | Alex Fernandez# | 1673 | 1990-1998 | |
| 61 | Chris Nabholz# | 1653 | 1990-1998 | |
| 62 | J.R. Richard | 1648 | 1976-1988 | |
| 63 | Juan Nieves# | 1639 | 1986-1998 | |
| 64 | Wilson Alvarez# | 1620 | 1990-1998 | |
| 65 | John Tudor | 1617 | 1979-1992 | |
| 66 | Pete Harnisch# | 1616 | 1989-1997 | |
| 67 | Tom Glavine# | 1615 | 1988-1998 | |
| 68 | Mike Morgan# | 1608 | 1979-1995 | |
| 69 | Roger Erickson | 1605 | 1978-1992 | |
| 70 | Steve Avery# | 1604 | 1990-1998 | |
| 71 | Charlie Leibrandt | 1597 | 1979-1990 | |
| 72 | Doug Drabek# | 1590 | 1987-1998 | |
| 73 | Bill C. Swift | 1583 | 1985-1996 | |
| 74 | Rick Aguilera# | 1574 | 1985-1998 | |
| 75 | Zane Smith# | 1546 | 1984-1997 | |
| 76 | Dennis Martinez | 1542 | 1976-1991 | |
| 77 | Mike Harkey# | 1538 | 1988-1998 | |
| 78 | Atlee Hammaker | 1532 | 1981-1991 | |
| 79 | Joe Johnson# | 1531 | 1985-1998 | |
| 80 | Mark Portugal# | 1463 | 1985-1998 | |
| 81 | Jim Abbott# | 1450 | 1989-1998 | |
| 82 | Joe Hesketh | 1447 | 1984-1993 | |
| 82 | Nolan Ryan | 1447 | 1976-1987 | |
| 82 | Randy Tomlin# | 1447 | 1990-1998 | |
| 85 | Rick Rhoden | 1446 | 1976-1992 | |
| 86 | Larry McWilliams | 1430 | 1978-1989 | |
| 87 | Denny Neagle# | 1428 | 1991-1998 | |
| 88 | Jay Tibbs# | 1417 | 1984-1998 | |
| 89 | Bruce Berenyi | 1412 | 1980-1993 | |
| 90 | Steve Carlton | 1410 | 1976-1985 | |
| 91 | Frank Wills# | 1408 | 1984-1998 | |
| 92 | Frank Castillo# | 1390 | 1992-1998 | |
| 93 | Pete Falcone | 1388 | 1976-1986 | |
| 93 | Steve Rogers | 1388 | 1976-1988 | |
| 95 | Mike LaCoss | 1383 | 1978-1991 | |
| 96 | Eric Plunk# | 1378 | 1986-1997 | |
| 97 | Tim Belcher# | 1371 | 1987-1997 | |
| 98 | Todd Van Poppel# | 1368 | 1991-1998 | |
| 99 | Tony Brizzolara | 1347 | 1980-1991 | |
| 100 | John Butcher | 1346 | 1980-1994 |
